There are many grades of gemstones you can buy on the web. I prefer buying gemstones that have nice clean clarity, especially if you are starting a new business.
These days it seems everyone is making wonderful handcrafted jewelry and some do not want to pay the prices of expensive semi-precious gemstones. 
Your customers will notice  if you have nice quality gems in your jewelry and it will show well in your hard work.
There are many neat handcrafted jewelry pieces out there on the web and competition is strict! The best way is to buy high grade gemstones and take good quality pictures.